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Reaksi glikolisis di bagi dua tahapTahap pertamaReaksi memerlukan energi (reaksi 15)Merupakan reaksi fosforilasi glukosa oleh ATP oleh bantuan enzim heksokinase Enzim ini bersifat dependen Mg2+ yang digunakan untuk pengkhelat ATP Glycolysis Step 1Hexokinase and glucokinase catalyzes irreversible phosphorylation of glucose (G6P).

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PK Glycolysis Derived from Greek words Glykys = Sweet Lysis = splitting During this process one molecule of glucose (6 carbon molecule) is degraded into two molecules of pyruvate (three carbon molecule) Free energy released in this process is stored as 2 molecules of ATP and 2 molecules of NADH.

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4 INTRODUCTION • GLYCOLYSIS is the sequence of 10 enzymecatalyzed reactions that converts glucose into pyruvate with simultaneous production on of ATP • In this oxidative process 1mol of glucose is partially oxidised to 2 moles of pyruvate • This major pathway of glucose metabolism occurs in the cytosol of all cell.

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1 GLIKOLISIS 2 Fate of glucose Completely oxidized to CO2 and H2OCellular respiration Converted to lactateCori cycle converts lactate back to glucose Converted.